WW,
I agree never get caught BETWEEN two or more attackers.
For a woman she would have to try and take out,move or remove, the smaller of the two.
As you said go for the one nearest to where you need to go to escape.
Targeting needs to be to incapcitate. (eyes,throat,face,ears,knees,elbows,groin)
Do not waste time on striking large muscled areas of the attackers body,especially a woman versus a man,no less two men.
Rip,shred,claw,knee,kick,elbow,gouge,crush or strike the targets that will lend the best results.
Good Luck